DISCOVER THE UBIQUINOL
Coenzyme Q10 (CoQ10) is an essential compound found naturally in virtually every cell in the human body, which is also known as ubiquinone.
CoQ10 is a lipid-soluble substance whose primary role is as an essential intermediate of the electron transport system in the mitochondria. Adequate amounts of CoQ10 are necessary for cellular respiration and ATP production. CoQ10 also functions as an intercellular antioxidant, and its presence was then demonstrated in all cell membranes and in blood, both in high- and in low-density lipoproteins, where it is endued with antioxidant properties
Numerous disease processes associated with CoQ10 deficiency can benefit from CoQ10 supplementation, including primary and secondary CoQ10 deficiencies, mitochondrial diseases, fibromyalgia (a syndrome characterized by pain and muscle stiffness), cardiovascular disease, neurodegenerative diseases, cancer, diabetes mellitus, atherosclerosis, migraine, male infertility, and periodontal disease.
It was reported patients who take cholesterol lowering drugs, which block the synthesis of CoQ10 inducing CoQ10 deficiency in the heart muscle, should make strong their heart with supplemental CoQ10.
Ubiquinol is the reduced, active form of ubiquinone and is found in almost every cell in our body. The human body uses CoQ10 by converting it into its active form (CoQH).
Being the active form, it is used directly by the body. Therefore, it acts faster than the standard form (CoQ10).
Ubiquinol plays an important role in preventing oxidative damage to membrane lipids and preventing the initiation and/or propagation of serum LDL (it is also called as bad cholesterol). Thus, it is a potent antioxidant.
From the age of 40, our body's ability to convert CoQ10 to CoQH decreases. Therefore, it becomes essential to take ubiquinol as a supplement.
Garrido-Maraver, J., Cordero, M. D., Oropesa-Ávila, M., Fernández Vega, A., De La Mata, M., Delgado Pavón, A., ... & Sánchez-Alcázar, J. A. (2014). Coenzyme q10 therapy. Molecular syndromology, 5(3-4), 187-197. Dallner, G., & Stocker, R. (2005). Coenzyme Q10. Encyclopedia of dietary supplements, 121-131. Langsjoen, P. H. (1994). Introduction to coenzyme Q10. Texas, University of Texas Medical Branch at Galveston http://faculty. washington. edu/ely/coenzq10. html (25.4. 2009). Garrido-Maraver, J., Cordero, M. D., Oropesa-Avila, M., Vega, A. F., de la Mata, M., Pavon, A. D., ... & Sanchez-Alcazar, J. A. (2014). Clinical applications of coenzyme Q10. Front Biosci (Landmark Ed), 19(4), 619-633. Ernster, L., & Forsmark-Andree, P. (1993). Ubiquinol: an endogenous antioxidant in aerobic organisms. The clinical investigator, 71, S60-S65. Frei, B., Kim, M. C., & Ames, B. N. (1990). Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations. Proceedings of the National Academy of Sciences, 87(12), 4879-4883. Evans, M., Baisley, J., Barss, S., & Guthrie, N. (2009). A randomized, double-blind trial on the bioavailability of two CoQ10 formulations. Journal of Functional Foods, 1(1), 65-73. Alf, D., Schmidt, M. E., & Siebrecht, S. C. (2013). Ubiquinol supplementation enhances peak power production in trained athletes: a double-blind, placebo controlled study. Journal of the International Society of Sports Nutrition, 10(1), 24.